MECHANISMS OF ATAXIA TELANGIECTASIA MUTATED (ATM) CONTROL IN THE DNA DAMAGE RESPONSE TO OXIDATIVE STRESS, EPIGENETIC REGULATION, AND PERSISTENT INNATE IMMUNE SUPPRESSION FOLLOWING SEPSIS

Mechanisms of Ataxia Telangiectasia Mutated (ATM) Control in the DNA Damage Response to Oxidative Stress, Epigenetic Regulation, and Persistent Innate Immune Suppression Following Sepsis

Cells have evolved extensive signaling mechanisms to maintain redox homeostasis.While basal levels of oxidants are critical for normal signaling, a tipping point is reached when the level of oxidant species exceed cellular antioxidant capabilities.Myriad pathological conditions are characterized by elevated oxidative stress, which can cause alterat

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Antagonistic gene activities determine the formation of pattern elements along the mediolateral axis of the Arabidopsis fruit.

The Arabidopsis fruit mainly consists of a mature ovary that shows three well defined territories that are pattern elements along the mediolateral axis: the replum, located at the medial plane of the flower, and the valve and the valve margin, both of lateral nature.JAG/FIL activity, which includes the combined functions of Outdoor Games JAGGED (JA

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PROTECTION AND PROMOTION OF PUBLIC HEALTH IN EU LAW

The paper presents overview of development of the principle of protection and promotion of public health in EU law and current legal framework together with legal and non legal instruments used to put this principle into practice.Protection Horse Stall Guards of public health comes a long way, but only since Treaty of Maastricht, there is a legal b

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